Zodiac sign was associated with outcome following TKA. When adjusting for confounding, Pisceans had significantly less of an improvement in OKS at both 1 (p=0.022) and 2 years (p=0.042) and also had a significantly lower risk of satisfaction at 2 years (odds ratio 0.41, p=0.043). When adjusting for confounding, Aries (p=0.031) had a greater improvement in EQ-5D at 1 year, although this was not maintained at 2 years. Aries and Gemini (0.366) had the worst and Pisces the best (0.595) pre-operative EQ-5D scores (p=0.038). There were no significant differences in gender (p=0.712), age (p=0.088), BMI (p=0.660), or pre-operative OKS (p=0.539). There were 509 patients (228 males and 281 females ) with a mean age of 70.9 years and a mean BMI of 30.3. Each patient's zodiac sign was assigned from their date of birth. Patient demographics, Oxford Knee Score (OKS), EuroQol 5-dimension (EQ-5D) (baseline, 1 and 2 years) and patient satisfaction scores (1 and 2 years) were collected. Patients undergoing primary TKA during a 2-year period (January 2019 to December 2020) were identified retrospectively. The aim of the study was to evaluate the effect of zodiac sign on patient-reported outcome measures (PROMS) following primary total knee arthroplasty (TKA). There are 12 signs of the zodiac, each attributed with its own specific personality traits, desires and attitudes.
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